Twinkle LB 970 Microplate Fluorometer

Berthold Technologies

Walk-away Solution

TheLB 931 Microplate Stacker can be used with the multi-detection readers Mithras and TriStar as well as the microplate fluorometer Twinkle. A barcode reader provides positive plate identification making the system a true walk-away solution for microplate reading. Quoted separately.

LB 931 Microplate Stacker

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LB 970

Twinkle Microplate Fluorometer

The dedicated fluorometer is using an optimized design for a variety of measurement modes to support academic and pharmaceutical research centers.

  • kinetics
  • scanning
  • dual ratio measurements
  • top reading
  • bottom reading
  • temperature control

make Twinkle a valuable instrument for any researcher using fluorescence in life science.

The measurement of different plate formats, e.g. up to 384 well microplates, filters, petri dishes or Terasaki plates is possible.

The high quality design is well suited for sensitive FRET assays.

Temperature Control

The instrument can be equipped with temperature control to establish ideal conditions for all cell based applications.

Fluorescence Optics

The Twinkle LB 970 Fluorometer provides highest sensitivity due to Single Photon Counting technology and extremely low noise Photomultiplier. For excitation a Tungsten halogen lamp is used. The instrument is standard equipped with filter pairs for FITC and Umbilliferone.

The fluorescence reading can be taken from the bottom or the top. The bottom reading is instrument of choice for measurements of adherent cells, coloured medium and lids to achieve the most efficient detection.


Especially in cell applications samples are heterogenously spread in the well. To measure the complete area, up to 100 individual measuremet points can be defined within the same well.


3 modes each with variable speed of the integrated shaker to enhance mixing and optimise sample distribution before measurement in long term kinetics.


Kinetic measurements can be performed up to 7 days.

Detection Devicelow noise, high sensitivity PMT in photon copunting mode
Excitation Sourcehalogen lamp, spectral range 340 - 700 nm
Plate Formats

6 - 384 well microplates
Terasaki plates
Petri dishes
filter membranes

Temperature Controlup to 40 °C
Shaking3 modes, 3 speeds
Scanningup to 100 data points per well
Kineticsminimum resolution 0.1 sec
maximum duration 7 days
AutomationRobot integration
stacker unit
Fluorescence<0.3 fmol FITC per well
Dimensions280 x 465 x 406 mm (H x W x D)
OSWin XP, Win Vista, Win 7
RegulationsCE, UL, CSA

LB 970 Twinkle Brochure (lb970_twinkle_brochure_(1).pdf, 175 Kb) [Download]